|
Symbol Name ID |
Acta2
actin alpha 2, smooth muscle, aorta MGI:87909 |
| Darker colors indicate more annotations |
| Human Phenotypes | Cerebral hemorrhage |
Subarachnoid hemorrhage |
Bruising susceptibility |
Abnormal left ventricle morphology |
Bicuspid aortic valve |
Dilated cardiomyopathy |
Cardiomegaly |
Right aortic arch |
Ascending aortic dissection |
Aortic aneurysm |
Abdominal aortic aneurysm |
Thoracic aortic aneurysm |
Aortic root aneurysm |
Ascending tubular aorta aneurysm |
Descending thoracic aorta aneurysm |
Aortic dissection |
Descending aortic dissection |
Aortic rupture |
Mucoid extracellular matrix accumulation |
Patent ductus arteriosus |
Carotid artery dilatation |
Carotid artery occlusion |
Carotid artery stenosis |
Anterior cerebral artery stenosis |
Middle cerebral artery stenosis |
Posterior cerebral artery stenosis |
Dilatation of the cerebral artery |
Moyamoya phenomenon |
Coronary artery aneurysm |
Coronary artery atherosclerosis |
Premature coronary artery atherosclerosis |
Coronary artery dissection |
Peripheral arterial stenosis |
Cystic medial necrosis |
Inflammatory arteriopathy |
Abnormal cerebral vascular morphology |
Stroke |
Ischemic stroke |
Stroke-like episode |
Transient ischemic attack |
Abnormal left ventricular function |
Aortic regurgitation |
Hypertension |
Raynaud phenomenon |
Hypovolemia |
Cutis marmorata |
Livedo reticularis |
Telangiectasia |
| Disease(s) Associated with ACTA2 | ||||||||||||||||||||||||||||||||||||||||||||||||
| Moyamoya disease | ||||||||||||||||||||||||||||||||||||||||||||||||
| thoracic aortic aneurysm |
| Mouse Phenotypes | abnormal aorta morphology |
abnormal aorta elastic tissue morphology |
decreased heart weight |
abnormal blood flow velocity |
abnormal systemic arterial blood pressure |
decreased systemic arterial systolic blood pressure |
increased vascular permeability |
decreased vasoconstriction |
|
| Availability | Mouse Genotype | ||||||||
| Acta2em1(IMPC)H/Acta2em1(IMPC)H | |||||||||
| Acta2tm1Rjs/Acta2tm1Rjs | |||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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